Regulation of Protein 4 . 1 R Interactions with Membrane Proteins by Ca
نویسندگان
چکیده
1. Abstract 2. Introduction 3. Techniques Used for Measuring Binding Affinity 4. Organization of the Erythrocyte Membrane Skeleton 4.1. Maintenance of Erythrocyte Shape 4.2. Maintenance of Erythrocyte Membrane Mechanical Properties 5. 4.1R as a Modulator in a Complex Membrane System 5.1. Facilitation of p55 Binding to GPC 5.2. Modulation of Ankyrin Binding to Transmembrane Proteins 5.3. Facilitation of Spectrin/Actin Interaction 6. Ca/CaM-Dependent Regulation of 4.1R Interactions 6.1. Variations in Intracellular Ca Level 6.2. 4.1R, a CaM-Binding Protein with Unique Features 6.3. Ca/CaM-Dependent Regulation of Membrane Protein Interactions 7. Functional Structure of 4.1R 7.1. Overview of 4.1R 7.2. 30kDa (FERM) Domain 7.2.1. Crystal Structure of 4.1R 30kDa (FERM) domain 7.3. 10kDa (SAB) Domain 7.4. 22/24kDa (CTD) Domain 8. At least Two Alternative Splicing Initiation Sites in One Single Gene 9. 4.1R homologues 10. Conclusion 11. Appendix 12. Acknowledgements 13. References
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